| | Conditions Treatments | Cold Flu Can you use a 23 gauge needle for flu shot? No. A 23 gauge needle is considered too large for a flu shot. The standard needle used for flu shots is a 25 gauge needle which is thinner and causes less pain. Cold Flu - Related Articles DOT: Biohazard Regulations Medicare Skilled Nursing Guidelines Chemotherapy Side Effects on the Eyes Primary Functions of Carbohydrates How to Process Kava Kava Why does malaria occur in some places more than others? How to File a Complaint Against a Dermatologist