Can cold sores spread while taking acyclocir?

While taking acyclovir, it is possible for cold sores to still spread, although the risk is reduced. Acyclovir is an antiviral medication that can help to shorten the duration and severity of cold sores, but it does not completely eliminate the virus from the body. Therefore, it is still possible for the virus to be transmitted to others through direct contact with the infected area, such as kissing or sharing utensils. It is important to practice good hygiene and avoid contact with others if you have an active cold sore to prevent spreading the virus.