How does MAOI help treat depression?

Monoamine oxidase inhibitors (MAOIs) are a class of antidepressants that work by inhibiting the action of the enzyme monoamine oxidase (MAO). MAO is responsible for breaking down certain neurotransmitters in the brain, including serotonin, norepinephrine, and dopamine. By inhibiting the action of MAO, MAOIs increase the levels of these neurotransmitters in the brain, which can help to improve mood in people with depression.

MAOIs have been shown to be effective in treating both major depressive disorder (MDD) and atypical depression. They are often used in people who have not responded to other antidepressants or who have not tolerated their side effects. MAOIs are generally taken once or twice a day, and they can take several weeks to start working.

MAOIs are associated with a number of side effects, including dizziness, headaches, nausea, diarrhea, constipation, anxiety, insomnia, and weight gain. They can also interact with certain foods and medications, so it is important to talk to your doctor about potential risks and benefits before starting MAOI treatment.

Despite their side effects, MAOIs can be an effective treatment for depression. They can provide relief from symptoms, improve mood, and help people to live more fulfilling lives.