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Imipramine Vs. Clomipramine Side Effects

Clomipramine and Imipramine are both tricyclic antidepressants that work by increasing the action of certain chemicals in the brain that are directly involved in mood and behaviors.

  1. Uses

    • Clomipramine is primarily used to treat obsessive-compulsive disorder and Imipramine is primarily used to treat depression and less frequently, bed-wetting in children.

    Common Side Effects

    • Clomipramine and Imipramine have similar common side effects, which include dizziness, drowsiness, dry mouth, headache, nausea, nightmares, sweating, tiredness, upset stomach, vomiting, weakness and changes in weight (loss or gain).

    Clomipramine Side Effects

    • Other associated common side effects with Clomipramine are reported as constipation, diarrhea, irritability and loss of appetite.

    Imipramine Side Effects

    • Imipramine users have also reported excitement, impotence, pupil dilation and sensitivity to sunlight as side effects.

    Warning

    • Both drugs have the same serious side effects, including a black-box warning from the Food and Drug Administration regarding the potential for patients to develop suicidal thoughts or behaviors in teenagers and young adults.

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