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Depression After Treatment With Sertraline

Depending on the cause of an individual's depression, medications such as Sertraline (Zoloft) may either be a short term solution or a permanent necessity. Most people will experience alleviation of symptoms with only mild side effects.

  1. Indications

    • Sertraline is an antidepressant in the SSRI class, and is used primarily for the treatment of major depressive disorder.

    Therapeutic Effects

    • Sertraline is a proven, effective treatment. While its mechanism of action is not well understood, it is known to have a significant effect on the levels of the neurotransmitter serotonin. The subjective effect is a dampening of negative emotion and an overall improvement in mood.

    Side Effects

    • Relative to other antidepressants, Sertraline's side effects are mild for most people, and generally dissipate after several weeks of use. Side effects include akathisia, dry mouth, somnolence and insomnia.

    Duration of Use

    • If the cause of the depression is a temporary, circumstantial issue, Sertraline will probably only be used until the circumstances---and thus the depression---resolve. If the depression is chemical in nature (i.e., inherited), Sertraline may be required permanently.

    Discontinuation

    • After a period of treatment, your medical provider may attempt to lower the dose or discontinue the treatment. This is done under close supervision, and if symptoms of depression begin to reappear, the treatment may resume.

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