Side Effects of 5-Htp

The dietary supplement 5-Htp increases the production of serotonin, a chemical that affects your appetite, sleep, sexual behavior, temperature and pain sensation. According to rxlist, it may effectively treat depression and fibromyalgia. Although it is available without a prescription, before taking 5-Htp you should be aware of possible side effects.
    • 5-Htp is available without a prescription.

    Gastrointestinal

    • Taking 5-Htp can result in gastrointestinal problems such as heartburn, diarrhea, constipation, flatulence, nausea, vomiting and stomach rumbling sensations. Individuals with chronic digestive conditions should not take 5-Htp.

    Cardiovascular Conditions

    • Taking 5-Htp can cause harmful side effects for those who have cardiovascular conditions such as post-heart attack, post-stroke or high blood pressure.

    Drug Interactions

    • There may be adverse reactions if 5-Htp is taken with medications such as antidepressants, cold medications containing dextromethorphan, meperidine (Demerol), pentazocine (Talwin), tramadol (Ultram), antibiotics, weight loss medications, tranquilizers and chemotherapy drugs. You should not consume alcoholic beverages while taking 5-Htp.

    Other Side Effects

    • Other side effects that may result from taking 5-Htp include muscle problems, sexual problems, rashes, headaches, flushing, edema and drowsiness.

    Considerations

    • It is not recommended that you take 5-Htp if you are pregnant or breastfeeding, if you are scheduled for surgery in the next couple of weeks or if you have Down syndrome.

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