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Lexapro Effects on the Elderly

Lexapro is a selective serotonin reuptake inhibitor (SSRI) used to treat depression and anxiety. It works to correct a chemical imbalance in the brain to relieve symptoms of severe depression: lack of energy, loss of interest, loss of sex drive, sleep disruption, overeating or loss of appetite. Like all drugs used to treat depression, Lexapro has side effects. This article addresses the concerns of elderly depression sufferers taking the drug.

  1. How Lexapro Works

    • SSRIs (selective serotonin reuptake inhibitors, the class of drugs to which Lexapro belongs) work by increasing the amount of serotonin active in the brain. Serotonin is a neurotransmitter, a chemical that sends signals in the brain. Serotonin affects appetite, mood and anger. It travels between the presynaptic cell and the postsynaptic receptor to do its work. Normally there is some absorption or "reuptake" of serotonin in the presynaptic cell before it reaches the postsynaptic receptor. SSRIs limit this reuptake, increasing the amount of serotonin delivered to the postsynaptic receptor.

    Common Side Effects

    • The side effects of Lexapro are generally mild and decrease after a few weeks of taking the drug. Side effects may include:
      Decrease or loss of appetite
      Nausea
      Dry mouth
      Sleeplessness
      Fatigue
      Sleepiness, yawning, tiredness
      Sweating
      Sexual disturbances (particularly inhibiting the ability of males to reach orgasm)

    Uncommon Side Effects

    • Some more unusual side effects may indicate an adverse or paradoxical (opposite) reaction to the drug. If any of these side effects are experienced, immediate medical attention may be necessary:
      Dizziness, especially when standing (due to low blood pressure)
      Agitation, panic attacks
      Low sodium in blood (causes feelings of physical weakness, mental confusion)
      Serious allergic reaction
      High fever
      Mania, hallucinations
      Seizures, tremors

    Side Effects for the Elderly

    • Lexapro can be prescribed to patients over 65 in a lower dose. The effects and side effects are the same as with younger patients.

    Before Taking Lexapro

    • Before taking Lexapro or any prescription drug, talk to a health professional. There may be interactions with a drug you are currently taking or with a pre-existing medical condition. It's always best to consult a doctor before putting something new in your body.

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