About Diabetes Type 3

In 2005, scientific research found a new type of diabetes called Type 3, "doubled diabetes" or "hybrid diabetes," and it is more difficult to diagnose and significantly more challenging to treat. This newfound disorder is likewise occasionally referred to as "diabetes 1½," or Type 3 diabetes.

Type 3 diabetes could hit at any age. Reportedly, doctors are discovering growing amounts of patients with Type 3, in which a person bears the symptoms of both type 1 and type 2 high sugar levels. Treatment becomes particularly challenging in children.

Type 3 Diabetes and the Brain

• Researchers have found that, similar to what happens in the pancreas, insulin is released in the hippocampus of the brain also. Any trouble with this secretion contributes to Type 3 diabetes. This impacts the regularization of sensory receptors in the brain.

  For example, if there are disruptions in the brain due to inadequate insulin being released to certain receptors, it could lead to kidney disorders. The kidneys need the insulin function in the brain for healthy urine output and function.

  Researches are also studying how a lack of insulin in the brain may be tied to Alzheimer's disease, which is thought to be related to Type 3 diabetes.

Importance of ADH

• The secretion of insulin in the hippocampus is critical for the endurance of brain cells. Abnormality could result in Alzheimer's disease. According to advanced studies, this disease becomes affiliated with Type 3 diabetes.

  The disorder is induced through instability in your brain that impacts the hypothalamus, which releases an anti-diuretic endocrine hormone called ADH, which checks the bulk of water in your urine.

  Your kidneys depend on the discharge of ADH to assure healthy urine production. To understand what induces Type 3 diabetes, you must realize how ADH is involved in kidney function.

ADH and Kidneys

• ADH is created in your hypothalamus and put in your pituitary gland for storage. Should your system sustain a water deficit, it must bring down water elimination. The pituitary gland performs this through cutting down on the water passed in your urine by discharging ADH.

  ADH orders the kidneys to cut back on the water transmitted within your urine. Without ADH, there is no regulator, and your kidneys continue eliminating additional water through your urine, inducing dehydration in your system.

  A disorder dissimilar from additional diabetes types evolves once things go amiss in the function of ADH. Once its release, storage and discharge become shook up in your system, you may acquire Type 3 diabetes.

More Research Needed

• Type 3 diabetes has lately been used to identify a flaw in insulin layers within the brain that can possibly be associated with Alzheimer's disease. Type 3 diabetes research likewise has described the reality that many patients with Type 1 high sugar levels become insulin-resistant over time, which is commonly associated with Type 2 diabetes.

  However, more research is needed before the medical community can treat Type 3 diabetes as well as the critical underlying causes.

Controversy

• The question of whether low brain insulin levels can trigger Alzheimer's and Type 3 diabetes began to surface in the scientific literature about 20 years ago, but the concept tapered off. In 2005, Suzanne la Monte, a Brown University Medical School neuropathologist, revisited the question. Grounded with two of her findings--that the hippocampus creates its own insulin and that Alzheimer's disease uses up its own insulin--she called the disorder's procedure "Type 3" diabetes.

  Nevertheless, denoting Alzheimer's disease as "type 3" diabetes is controversial, particularly inside the diabetes medical community, and will remain so until more comprehensive research and findings are available.