How Does Rybelsus Control Type 2 Diabetes?

Rybelsus (semaglutide) is a once-weekly injectable medication used to improve glycemic control in adults with type 2 diabetes. It belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. Here's how Rybelsus works to control type 2 diabetes:

1. Stimulates Insulin Secretion: GLP-1 is a natural hormone produced in the gut after meals. It plays a role in regulating blood sugar levels. Rybelsus mimics the effects of GLP-1 by binding to GLP-1 receptors in the pancreas. This stimulates the beta cells in the pancreas to release insulin, which helps lower blood sugar levels.

2. Slows Gastric Emptying: Rybelsus also delays the emptying of the stomach (gastric emptying). When food stays in the stomach for a longer time, it is digested and absorbed more slowly. This helps slow the rise in blood sugar levels after meals.

3. Reduces Glucagon Production: Glucagon is another hormone produced by the pancreas. It has the opposite effect of insulin, raising blood sugar levels. Rybelsus reduces the secretion of glucagon, particularly after meals, which further prevents excessive blood sugar elevation.

4. Improves Insulin Sensitivity: Over time, Rybelsus can enhance the body's sensitivity to insulin. This means that the cells in the body become more responsive to insulin, allowing them to better absorb glucose from the bloodstream, leading to lower blood sugar levels.

5. Reduces Food Intake and Body Weight: Rybelsus has been shown to reduce appetite and promote feelings of fullness, which may lead to reduced food intake and weight loss. Weight management is important in managing type 2 diabetes as it can improve insulin sensitivity and overall glycemic control.

Rybelsus is typically used in combination with other diabetes medications, such as metformin, and lifestyle modifications that include a healthy diet and regular exercise. It is important to follow the prescribed dosing schedule and make healthy lifestyle choices to achieve optimal blood sugar control with Rybelsus.