Difference between insulin novarapid and human actrapid?

Insulin novarapid (insulin aspart) and human actrapid (human insulin) are both short-acting insulins used to manage blood sugar levels in individuals with diabetes. Both are injected into the body, however there are some key differences between the two:

1. Speed of Action: Insulin novarapid is known for its rapid onset of action, typically taking about 10-20 minutes to reach its peak effect. This makes it ideal for managing blood sugar levels around meal times, as it can closely mimic the release of insulin that occurs naturally after eating. Human actrapid, on the other hand, has a slightly slower onset of action, taking about 30-60 minutes to reach its peak effect.

2. Duration of Action: The duration of action refers to the length of time the insulin remains active in the body and continues to lower blood sugar levels. Insulin novarapid's duration of action is shorter compared to human actrapid. It usually lasts for about 3-5 hours, making it suitable for managing blood sugar levels during meals or for adjusting insulin doses more frequently. Human actrapid, on the other hand, has a longer duration of action, lasting about 6-8 hours. It is more suitable for individuals who may require longer-lasting insulin coverage or for those who are less prone to rapid blood sugar fluctuations.

3. Potential Side Effects: In terms of potential side effects, both insulins are generally well-tolerated, but there can be some differences:

- Insulin novarapid may cause a slightly higher risk of hypoglycemia (low blood sugar), due to its faster onset and shorter duration of action.

- Human actrapid may cause allergic reactions, such as skin rash or itching, more frequently compared to insulin novarapid, although these reactions are relatively rare.

It's important to consult with your doctor to determine which type of insulin, including novarapid and actrapid, is the most appropriate for your specific condition, lifestyle, and insulin needs. Your healthcare professional will consider your blood glucose control goals, meal patterns, and individual response to insulin when making treatment recommendations.