Mechanism of insulin zinc suspn in type 1 diabetes?

Insulin zinc suspension (also known as lente insulin or ultralente insulin) is a type of long-acting insulin that is used to manage type 1 diabetes. It is made up of a mixture of zinc and insulin crystals that are suspended in a water-based solution. When injected, the insulin crystals slowly dissolve and release insulin into the bloodstream, providing a steady supply of the hormone over a period of 24 to 48 hours.

Here is how insulin zinc suspension works in the body:

* After injection, the insulin crystals are taken up by macrophages (a type of white blood cell) at the injection site.

* Inside the macrophages, the insulin crystals are broken down into smaller molecules that can be absorbed into the bloodstream.

* The insulin molecules then bind to receptors on cells throughout the body, allowing glucose to enter the cells and be used for energy.

* Insulin also helps to inhibit the breakdown of glycogen (stored glucose) in the liver, and promotes the synthesis of glycogen and fatty acids.

* By providing a steady supply of insulin, insulin zinc suspension can help to control blood sugar levels and prevent complications of diabetes, such as heart disease, kidney disease, and blindness.

Insulin zinc suspension is typically taken once or twice daily, depending on the individual's needs. It is important to follow the doctor's instructions carefully when taking insulin zinc suspension, as the dose and timing of injections can vary from person to person.