What Is the Medicine Nexium For?

Nexium is a prescription drug used to treat gastroesophageal reflux disease (GERD), stomach or upper intestinal ulcers, and other conditions where excess stomach acid plays a role. Nexium has a number of side effects and some interactions and cautions.

Definition

• Nexium is a name brand medicine for the generic drug, esomeprazole. It belongs to a class of medications known as proton-pump inhibitors (PPIs).

How it Works

• Nexium works by stopping the production of stomach acid; it interferes with the proton pump in the mucus lining of the stomach at the final stage of acid production. Nexium can turn off stomach acid production in one hour.

Side Effects

• According to MedlinePlus, side effects may include constipation, diarrhea, dry mouth, gas, headache, nausea and stomach pain. More serious side effects include blisters or peeling skin, difficulty swallowing or breathing, hives, hoarseness, itching, a rash and swelling of the ankles, feet, hands, face, throat, tongue, eyes, lips, and the lower legs.

Interactions

• Nexium may increase the effects of certain drugs like warfarin, and interfere with the absorption of iron, ampicillin, digoxin and more. Combining Nexium with aspirin may increase gastric side effects.

Cautions and Warnings

• Nexium should not be taken if you are sensitive or allergic to any of its ingredients. It is not recommended for the treatment of GERD beyond 8 to 16 weeks.

Special Population

• Women who are pregnant, plan to become pregnant or are breastfeeding need to tell their doctor before using Nexium. If your doctor considers the drug crucial, it is important to weigh the benefits against the risks.