Side Effects of Cascara Sagrada

Cascara sagrada is the dried bark of a small tree that grows in the Pacific Northwest. Available in capsules, liquid extract and tea, cascara sagrada functions as a laxative, and people take it to relieve occasional constipation.

Stomach Upset

• The most common side effect associated with cascara sagrada is upset stomach. Other side effects include abdominal cramps and nausea.

Diarrhea

• Because of the laxative effect, cascara sagrada can cause diarrhea, which in turn can result in fluid and electrolyte imbalances, and vitamin and mineral deficiencies.

Constipation

• As with other laxatives, chronic use of cascara sagrada can cause dependency, causing constipation unless using the medication. People should not use cascara sagrada longer than seven consecutive days.

Melanosis Coli

• Chronic use of cascara sagrada also can cause a condition called melanosis coli, which involves staining or darkening of the colonic mucosa. This usually is not a serious side effect, but it can reduce bowel function.

Urine Color

• Cascara sagrada can change the color of urine to pink, red, violet, brown or black.

Considerations

• People with certain health conditions should not take cascara sagrada. These include appendicitis, Crohn's disease, diverticular disease, rectal bleeding, ulcerative colitis or a history of intestinal blockage.