What Is Asacol?

Asacol is one of the brand names for the drug mesalamine. It is used to minimize inflammation of the bowel caused by ulcerative colitis, also known as inflammatory bowel disease, and other conditions that cause bowel inflammation such as Crohn's Disease. The drug is a non-steroidal and when taken regularly it can reduce bowel inflammation so the colon can begin healing itself. Asacol is available by prescription only and comes in an extended-release capsule, delayed-response tablet, an enteric-coated tablet, or a plain tablet.

Function

• Asacol is coated with a special covering. This covering is designed so it will only dissolve when it is in an area of the body that has a pH level of 7 or higher. Because of this, the drug is easy to swallow and it will not dissolve in the stomach. The drug passes from the stomach into the intestines, where it eventually settles in the colon. Once in the colon, the special covering melts away and the anti-inflammatory medication is absorbed, reducing inflammation of the colon and the rectum.

Dosage and Usage Guidelines

• Dosage varies from patient to patient and is determined by the prescribing physician based on the patient and the condition that is causing the bowel inflammation. Patients who are prescribed the delayed-release form of Asacol should take the medication with food. All other forms of the medication can be taken with or without food. Capsules and tablets should not be crushed, chewed, broken, opened, or dissolved in water. They must be swallowed whole. The drug should be taken as prescribed and the medication should not be stopped without first consulting the prescribing physician.

Side Effects

• Asacol may have unwanted side effects. Individuals who develop stomach pain, fever, severe headache, bloody diarrhea, itching, skin rash, anxiety, back pain, pale, blue-tinged or yellow-tinged skin, chest pain, fast heartbeat, chills, nausea or vomiting, yellow eyes, abdominal swelling, and/or unusual weakness should contact their doctor immediately as the medication may have to be discontinued. Symptoms of Asacol overdose include confusion, severe drowsiness, severe diarrhea, fast breathing, deep breathing, dizziness, hearing loss or ringing in the ears and/or headache. Common side effects can include mild headache, mild stomach pain, mild diarrhea, runny nose, sneezing, flatulence, joint and back pain, acne, loss of hair and loss of appetite.

Considerations

• Individuals who are taking Asacol should not take antacids while they are taking the extended-release capsules. When these two medications are combined, it can alter the amount of Asacol that is released. Individuals who take the delayed-release tablets or the extended-release capsule should know they may see part of the tablets or capsules in their stools.

Warning

• Taking Asacol with certain medications can increase the risk of side effects. Prescribing physicians should be aware of all medications you take so the best treatment can be given to you.