What can occur when B-lymphocytes remain in the digestive tract?

When B-lymphocytes remain in the digestive tract, they can differentiate into plasma cells, which produce antibodies. These antibodies can bind to antigens in the digestive tract, such as those found on bacteria or food particles. This binding can lead to the activation of the immune system, resulting in inflammation and damage to the digestive tract. This condition is known as inflammatory bowel disease (IBD).