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Amyloidosis Information

Amyloidosis is the name given to a group of diseases that cause the accumulation of protein deposits on the organ systems of the body. Although rare, amyloidosis is a serious, life-threatening condition.

  1. Symptoms

    • Symptoms associated with amyloidosis include ankle and leg swelling, fatigue and weakness, weight loss, diarrhea and constipation, feeling full quickly when eating, shortness of breath, tingling or numb hands and feet, tongue enlargement, thick skin, easy bruising, purple patches around the eyes, swallowing problems, irregular heartbeat and protein in the urine.

    Types

    • Amyloidosis is divided into four types that include primary and secondary amyloidosis, familial amyloidosis, and other types of amyloidosis.

    Associated Conditions

    • Conditions associated with amyloidosis include carpal tunnel syndrome, cardiomyopathy, kidney failure, malabsorption and gastrointestinal reflux disease.

    Diagnosis

    • A physician will perform a physical exam, blood and urine tests to help confirm amyloidosis, but the only definitive test is a tissue biopsy.

    Treatment

    • Treatment for amyloidosis includes chemotherapy for abnormal plasma cells, stem cell transplantation and treatment of underlying conditions.

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