What are diseases caused by D.N.A?
Diseases caused by DNA damage include:
1. Inherited genetic disorders: Caused by mutations passed from parents to offspring, these disorders include cystic fibrosis, sickle cell anemia, hemophilia, and Huntington's disease.
2. Cancer: Mutations in DNA can lead to uncontrolled cell division and the formation of tumors. Exposure to carcinogens, such as ultraviolet radiation and chemicals, can also cause DNA damage and contribute to cancer development.
3. Neurodegenerative disorders: Diseases like Alzheimer's and Parkinson's are associated with mutations or errors in DNA repair mechanisms that affect brain cells.
4. Premature aging syndromes: Disorders such as Werner syndrome and progeria are characterized by accelerated aging due to abnormalities in DNA repair processes.
5. Fragile X syndrome: A genetic disorder caused by abnormalities in the FMR1 gene, resulting in intellectual disabilities and physical characteristics.
6. Rett syndrome: A neurodevelopmental disorder primarily affecting girls, caused by mutations in the MECP2 gene.
7. Down syndrome: A chromosomal disorder caused by the presence of an extra copy of chromosome 21, leading to intellectual disabilities and distinct physical features.
8. Sickle cell anemia: A blood disorder caused by a mutation in the beta-globin gene, leading to sickle-shaped red blood cells and blockages in blood vessels.
These diseases highlight the critical role of DNA integrity in maintaining overall health and well-being. Genetic research and advances in understanding DNA repair mechanisms play a crucial role in developing targeted therapies and strategies to prevent or manage these diseases.