What can dariers disease do to you?
Darier's disease, also known as Darier-White disease or keratosis follicularis, is a rare autosomal dominant genetic skin condition. It is caused by mutations in the ATP2A2 gene, which encodes a calcium pump in the endoplasmic reticulum. This mutation leads to abnormal keratinization of the skin, resulting in the formation of rough, scaly patches and bumps on the skin.
Common symptoms of Darier's disease include:
Skin lesions: Darier's disease is characterized by the development of skin lesions that are typically red, scaly, and crusty. These lesions often occur on the face, scalp, chest, back, and extremities.
Greasy or oily skin: People with Darier's disease may experience excessive oiliness or greasiness of the skin, particularly in the affected areas.
Itching and discomfort: The skin lesions associated with Darier's disease can cause itching, irritation, and discomfort, especially when they become inflamed or infected.
Hyperkeratosis: Darier's disease is associated with hyperkeratosis, which refers to the thickening of the outermost layer of the skin (the epidermis). This thickening can lead to the development of rough, scaly patches and bumps on the skin.
Nail changes: Darier's disease can affect the nails, causing them to become brittle, thickened, and discolored.
Darier's disease can also lead to other complications, such as:
Bacterial infections: The skin lesions associated with Darier's disease can become infected with bacteria, leading to inflammation, discomfort, and further skin damage.
Scarring: Severe or recurrent skin lesions can lead to scarring, which can affect the appearance and texture of the skin.
Psychological impact: The visible skin lesions associated with Darier's disease can cause significant psychological distress, affecting a person's self-esteem, social interactions, and quality of life.
Darier's disease is a chronic condition, meaning it persists over a long period of time. While there is no cure, treatment options can help manage the symptoms and improve the quality of life for those affected by this condition.