Who said the desperate disease requires a dangerous remedy?

The phrase "desperate disease requires a dangerous remedy" is often attributed to Hippocrates, the ancient Greek physician who is considered the founder of modern medicine. Hippocrates lived in the 5th century BCE and his teachings had a profound impact on the development of Western medicine. The phrase is taken from his aphorism 6 in Section I of the book known as Epidemics: "For extreme diseases, extreme methods of cure, as to restriction, are most suitable."