What are the symptoms of fabry disease?

Symptoms in males

- Painful burning sensations in your hands and feet (acroparesthesias).

- Dark red, raised skin lesions (angiokeratomas) that develop in clusters.

- Clouding of the cornea (corneal opacity) that usually affects both eyes.

- Kidney disease.

- Heart disease — including thickening of the heart muscle (hypertrophic cardiomyopathy) and abnormal heart rhythms.

- Strokes.

- Gastrointestinal problems — such as diarrhea and abdominal pain.

- Hearing loss.

Symptoms in females

Women who have Fabry disease typically have milder signs and symptoms than do men — or they might not have symptoms until later in life. Signs and symptoms of Fabry disease in women can include:

- Tingling or burning pain in hands and feet

- Skin rashes

- Kidney disease

- Heart disease

- Gastrointestinal problems

- Hearing loss