What particular system of the body is affected by Malaria?

Malaria primarily affects the circulatory system and the red blood cells, causing symptoms such as fever, chills, and anemia. The parasite responsible for malaria, Plasmodium, invades and multiplies within red blood cells, leading to their rupture and the release of toxic substances. This destruction of red blood cells can lead to anemia, where the body does not have enough healthy red blood cells to carry oxygen to cells and tissues. Additionally, the infection can cause inflammation and damage to blood vessels, contributing to the overall impact of malaria on the circulatory system.