Neuropathy in Parkinson's Disease

Neuropathy is a condition marked by nerve damage. Parkinson’s disease can trigger autonomic neuropathy, which affects the peripheral nerves that communicate with the brain and spinal cord to control many important functions.

Parkinson's Disease and Autonomic Neuropathy

• Parkinson’s disease affects dopamine production—an important chemical messenger in the brain. This affects normal communication between the peripheral nerves and brain, which ensures proper functioning of all organs and systems. This impaired communication damages these important nerves, leading to autonomic neuropathy.

What is Autonomic Neuropathy?

• Autonomic neuropathy damages the nerves involved in regulating the heart, respiration, blood pressure, digestion and smooth muscles, among others.

Symptoms

• Symptoms will depend on what nerves have been damaged. They might include problems with digestion, urination and sexual function, fainting upon standing and abnormal sweating, according to the Mayo Clinic

Managing Parkinson's Disease

• Treating Parkinson’s disease comprises the primary treatment for the resulting autonomic neuropathy. Properly managing the underlying condition can slow progression and promote nerve regeneration, according to the Mayo Clinic. Drugs to improve dopamine production and/or function include Levodopa, Miraprex and Requip.

Treating Autonomic Neuropathy

• Certain treatments can manage the symptoms that might result from autonomic neuropathy and will depend on what areas of the body have been impacted. Doctors will prescribe medications or recommend lifestyle changes to deal with symptoms like gastrointestinal upset, urinary problems and low blood pressure.