What can happen if you take citalopram with amphetamine?

Serotonin syndrome

Citalopram is a selective serotonin reuptake inhibitor (SSRI), which means that it increases the amount of serotonin in the brain. Amphetamine is a stimulant that also increases the amount of serotonin in the brain. Taking citalopram with amphetamine can lead to serotonin syndrome, which is a potentially life-threatening condition. Symptoms of serotonin syndrome include:

* Agitation

* Confusion

* Diarrhea

* Fever

* Hallucinations

* Increased heart rate

* Muscle rigidity

* Seizures

* Tremor

Cardiotoxicity

Amphetamine can cause heart problems, such as increased heart rate and blood pressure. Citalopram can also cause heart problems, such as QT prolongation. Taking citalopram with amphetamine can increase the risk of heart problems.

Stroke

Amphetamine can increase the risk of stroke. Citalopram can also increase the risk of stroke. Taking citalopram with amphetamine can further increase the risk of stroke.

Death

Serotonin syndrome and cardiotoxicity can both be fatal. Taking citalopram with amphetamine can increase the risk of death.

If you are taking citalopram, you should not take amphetamine. If you are taking amphetamine, you should not take citalopram.