Why does lasix cause ringing in the ears?

Ototoxicity

Ototoxicity is a side effect of some medications, including furosemide (Lasix), which can damage the inner ear and lead to hearing loss, tinnitus (ringing in the ears), or vertigo (a spinning sensation).

The exact mechanism by which furosemide causes ototoxicity is not fully understood, but it is thought to be related to the drug's ability to inhibit the reabsorption of sodium and chloride ions in the loop of Henle in the kidney. This can lead to an increase in the concentration of these ions in the endolymph, the fluid that fills the inner ear, which can disrupt the normal function of the hair cells and other structures in the ear.

Ototoxicity is more likely to occur in people who take high doses of furosemide or who have underlying kidney disease. It is also more common in people who are exposed to loud noises or who have a history of ear problems.

If you experience ringing in the ears or other hearing problems while taking furosemide, it is important to talk to your doctor. They may recommend reducing the dose of the drug or switching to a different medication.

Here are some tips for preventing ototoxicity from furosemide:

* Take the lowest dose of furosemide that is effective for you.

* Avoid taking furosemide with other medications that can also cause ototoxicity, such as aspirin, ibuprofen, or aminoglycoside antibiotics.

* Protect your ears from loud noises.

* See your doctor regularly for hearing tests if you are taking furosemide for a long time.