What is a type of degenerative disease cause be dominant allele?

Huntington's disease is a type of degenerative disease caused by a dominant allele. It is an autosomal dominant neurodegenerative disorder that affects muscle coordination and cognition. The disease is caused by a mutation in the huntingtin gene (HTT) that results in the production of a mutant protein called huntingtin. This mutant protein damages nerve cells in the brain, leading to symptoms such as involuntary movements, difficulty walking, and problems with thinking and memory. Huntington's disease is typically inherited from one affected parent, although in rare cases, it can occur due to a new mutation in the HTT gene.