What causes high levels of Microsomal AB?

Elevated levels of microsomal AB (MAB) can be caused by several factors. Some of the most common causes include:

Microsomal Antibody Disease: This is a condition where the body produces antibodies that target the liver's microsomal enzymes. These enzymes are responsible for metabolizing drugs and other chemicals, so when they are inhibited, it can lead to a build-up of toxic substances in the liver.

Drug Interactions: Certain medications can interfere with the liver's ability to properly metabolize drugs and toxins. This can lead to a build-up of MAB and cause liver damage. Some of the medications that have been associated with elevated MAB levels include:

- Anticonvulsants

- Barbiturates

- Rifampin

- Isoniazid

- Ethanol

Hepatitis: Liver inflammation, caused by various factors like viral infections or autoimmune disorders, can lead to elevated levels of MAB as a result of impaired liver function.

Genetic Factors: Some people may be genetically predisposed to developing elevated MAB levels.

Liver Cirrhosis: Advanced liver damage due to cirrhosis can result in elevated levels of MAB due to the compromised liver function and decreased production of proteins involved in the metabolism of drugs and toxins.

Other Medical Conditions: Certain medical conditions, such as liver cancer, kidney failure, and hypothyroidism, can also contribute to elevated MAB levels.

It's important to note that elevated MAB levels alone don't always indicate a serious medical condition. However, if you have persistent or high levels of MAB, it's important to consult a doctor for further evaluation to determine the underlying cause and receive appropriate treatment.