Is it normal for your big toenails to randomly turn purple and blue fall off?

It is not normal for your big toenails to randomly turn purple and blue and fall off. This could be a sign of a serious underlying medical condition, such as a fungal infection, peripheral artery disease, or a vitamin B12 deficiency.

You should see a doctor right away if you experience this. In the meantime, there are some things you can do to help relieve your symptoms, such as keeping your feet clean and dry, applying antifungal cream, and taking over-the-counter pain relievers.