Extracellular Matrix and Hair

Hair forms, grows and dies in a regular three-stage cycle. All three stages of the cycle rely heavily on connective tissues in the scalp called the extracellular matrix.
  1. Extracellular Matrix

    • The Medical Biochemistry Page defines an extracellular matrix as a complex web of connective tissues. In the scalp, this matrix assists in the growth, shedding and regrowth of hair.

    Hair Growth Stages

    • According to the Keepmyhair.ca website, the life cycle of a hair consists of three main stages known as anagen, catagen and telogen.

    Anagen

    • When a new hair forms during anagen, the scalp's cells, blood supply and extracellular matrix convey signals to the hair follicle regulating the speed of hair growth.

    Catagen

    • In this transitional stage, the extracellular matrix uses its fibers to move the bulb of the dying hair follicle to the surface of the skin.

    Telogen

    • After the hair falls out, the extracellular matrix continues to act as a chemical and structural bridge between the bulb and its blood supply. A chemical message from the matrix then causes stem cells to reawaken and form a new hair follicle in place of the previous one.

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