Why diseases such as hemophilia affects the males more than female?

Haemophilia is a genetic disorder in which the blood does not clot properly. This is due to a deficiency in the clotting proteins known as clotting factors. Haemophilia is an X-linked recessive disorder, which means that the gene for haemophilia is located on the X chromosome. Males are more commonly affected by haemophilia because they only have one X chromosome, while females have two.

In order for a female to be affected by haemophilia, she must inherit two copies of the haemophilia gene, one from each parent. This is much less likely to happen than a male inheriting one copy of the gene from his mother.

Males who inherit one copy of the haemophilia gene are said to be haemophiliac. They will have mild to severe symptoms of the disorder, depending on the amount of clotting factor that is missing.

Females who inherit one copy of the haemophilia gene are said to be carriers. They will not have any symptoms of the disorder, but they can pass the gene on to their children.

Haemophilia is a serious disorder, but it can be managed with treatment. Treatment includes clotting factor replacement therapy, which can help to prevent bleeding episodes.