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Is Hep A Vaccine a Live Virus?

Live virus vaccines have been developed against hepatitis A virus (HAV); however, those currently used contain an inactivated form of the virus. Though inactivated, a full course of HAV vaccine has been shown to be effective in protecting against the virus in the long term, according to the World Health Organization (WHO).

  1. Features

    • Although cultured in different ways, the available HAV vaccines use a form of the virus which has been inactivated through the use of formalin (a combination of formaldehyde, water and an alcohol), according to the WHO.

    Effects

    • The inactivated form of the virus in the HAV vaccine causes the immune system to produce antibodies against the virus, which can protect an individual if exposed to the virus in the future, according to the Centers for Disease Control and Prevention (CDC).

    Time Frame

    • According to Medline Plus, a vaccinated person usually develops protection against HAV within two weeks after vaccination. A booster shot should be administered six to 12 months later to provide long-lasting protection.

    Considerations

    • Although the WHO reports that the vaccine against HAV has been shown to be safe, an allergic reaction could occur, and people who are known to be seriously allergic to any part of the vaccine should not be vaccinated, according to Medline Plus.

    Warning

    • Other people who should not be vaccinated against HAV include women who are pregnant or nursing and children under age 1, according to Medline Plus. People who are ill when they are scheduled to receive the vaccine should wait until they are healthy to be vaccinated.

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