Why would a person have no immunity to Hepatitis B after having the hep b vaccination series done twice?

There are a few possible reasons why a person might not have any immunity to Hepatitis B after having the hep B vaccination series done twice.

* The person may not have responded to the vaccine. This can happen for a variety of reasons, including:

* Genetic factors: Some people may have genetic variations that make them less likely to respond to the vaccine.

* Immune system problems: People with certain immune system disorders, such as HIV/AIDS, may not be able to respond to the vaccine.

* Medications: Certain medications, such as chemotherapy and steroids, can suppress the immune system and make it less likely to respond to the vaccine.

* Age: Older adults may be less likely to respond to the vaccine than younger adults.

* Obesity: Obese people may be less likely to respond to the vaccine than people who are not obese.

* The person may not have received all three doses of the vaccine. The Hepatitis B vaccine is given in a series of three doses, and a person must receive all three doses in order to be fully protected. If a person misses one or more doses, they may not be fully protected against the virus.

* The person may have been exposed to the virus before they were vaccinated. If a person is exposed to the Hepatitis B virus before they are fully vaccinated, they may not be able to develop immunity to the virus.

If you have had the Hepatitis B vaccine series done twice and you are still not immune to the virus, it is important to talk to your doctor to find out why. Your doctor may recommend that you get tested for the Hepatitis B virus or that you get additional doses of the vaccine.