Does Raise Risk Blood Clots?

Can Testosterone Replacement Therapy Increase the Risk of Blood Clots?

Testosterone replacement therapy (TRT) is a treatment option for men who have low testosterone levels. TRT can help to improve a man's sexual function, energy levels, and mood. However, there is some concern that TRT may increase the risk of blood clots.

What is the evidence?

There is some evidence to suggest that TRT may increase the risk of blood clots. For example, a study published in the journal JAMA Internal Medicine found that men who used TRT were more likely to experience blood clots than men who did not use TRT. The study found that the risk of blood clots was highest in men who used high doses of TRT.

Another study, published in the journal The Lancet, found that men who used TRT were more likely to experience blood clots than men who did not use TRT. However, this study did not find a significant difference in the risk of blood clots between men who used high doses of TRT and men who used low doses of TRT.

What is the mechanism?

It is not clear why TRT may increase the risk of blood clots. However, it is thought that TRT may increase the levels of certain hormones in the body that can lead to blood clotting.

What are the recommendations?

The American Urological Association (AUA) recommends that men who are considering TRT should be evaluated for their risk of blood clots. The AUA also recommends that men who are using TRT should be monitored for signs of blood clots.

If you are considering TRT, talk to your doctor about the potential risks and benefits of this treatment.