Does Paine medications raise blood pressure?

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).

NSAIDs, such as aspirin, ibuprofen (Advil, Motrin), and naproxen (Aleve), can cause the kidneys to retain sodium and water. This can lead to an increase in blood pressure. Additionally, NSAIDs may also inhibit the production of a substance called prostaglandin I2, which has a blood pressure-lowering effect.

Opioid Painkillers

Opioid painkillers, such as codeine, oxycodone (OxyContin), and morphine, can cause blood pressure to rise by increasing the activity of the sympathetic nervous system and by causing fluid retention.

Muscle Relaxants

Some muscle relaxants, such as cyclobenzaprine (Flexeril) can also cause blood pressure to rise.

It is important to note that the effect of pain medications on blood pressure can vary from person to person. If you are taking pain medication and you are concerned about your blood pressure, be sure to talk to your doctor.