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Side Effects of Truvada

Truvada is a combination of two anti-viral drugs, emtricitabine and tenofovir. This medication is used along with other anti-viral drugs to treat human immunodeficiency virus (HIV) and slow its growth. Many side effects are possible.

  1. Common Side Effects

    • Clinical studies have only evaluated Truvada side effects along with other drugs, since the medication is intended for use with others as part of a drug "cocktail." In these studies, as detailed by eMedTV, the most common side effects associated with Truvada in combination with other drugs were dizziness, nausea, diarrhea, fatigue and headaches, occurring in 5 percent to 8 percent of participants.

    Less Common Effects

    • Less common side effects in the studies included sinus infection, upper respiratory tract infection, sore throat, runny nose, drowsiness, abnormal dreams and vomiting.

    Body Fat

    • Truvada can cause changes in the distribution of body fat. This typically results in increased fat in the upper back and stomach, and less fat in the arms and legs.

    Liver and Blood Disorders

    • Rarely, Truvada can cause severe and life-threatening liver and blood disorders, such as lactic acidosis. Symptoms include jaundice, dark urine, abdominal pain, rapid or shallow breathing, muscle aches, severe drowsiness and weakness. Truvada can be problematic for patients with hepatitis or cirrhosis.

    Kidney Issues

    • Some patients with a history of kidney disorders cannot take Truvada because it can worsen these problems.

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