Characteristics of Cushing's Disease

Cushing's syndrome, also called Cushing's disease, may develop naturally or can be caused by long term or over use of synthetic oral steroids. The characteristics of Cushing's syndrome include significant changes in physical appearance and the development of conditions that may lead to serious chronic diseases such as diabetes, according to the Mayo Clinic.

Skin Changes

• Acne, thinning of the skin, dark stretch marks, bruising without force or injury, and flushing of the face are common skin changes characteristic of Cushing's syndrome.

Hirsutism

• In both men and women, a common characteristic of Cushing's syndrome is hirsutism, which is the growth of thicker or darker hair on the body and head.

Mental Changes

• Cushing's syndrome may cause severe mental changes including major depression, anxiety disorders, irrational and unpredictable behavior.

Osteoporosis

• High amounts of steroids in the body characteristic of Cushing's syndrome can cause bone damage and loss over a long period of time, resulting in osteoporosis.

Weight Gain

• Cushing's syndrome may cause weight gain in the abdomen and a rounding of the face, as well as a build up of fat between the shoulders that resembles a hump.

Glucose Intolerance

• People with Cushing's syndrome may develop glucose intolerance, which if not treated, can lead to diabetes.

Increased Blood Pressure

• Blood pressure that was previously normal or managed with medications may suddenly increase in people with Cushing's syndrome.