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Cushing's Disease Signs

Cushing's disease is a condition caused by abnormally high levels of the hormone cortisol circulating throughout the bloodstream. It can be caused by taking too many corticosteroids or by a tumor that secretes cortisol or other hormones which cause cortisol to be made. Because Cushing's disease alters hormone levels, it has a myriad of symptoms.

  1. Changes in Weight

    • Often the first symptom observed in Cushing's disease is sudden weight gain. It typically affects the trunk the most.

    Other Weight Gain Features

    • People with Cushing's disease often develop a small pad at the back of the neck along the collar bone, known as a buffalo hump. They may also develop a roundish face, which is known as moon face.

    Bruising

    • Cushing's disease often leads to capillary dilation as well as the skin becoming thinner. This causes bruising.

    Other Hormonal Issues

    • The effects of Cushing's disease can cause excessive urination, high blood pressure and resistance to insulin (leading to diabetes).

    Psychological Effects

    • The hormonal imbalance caused by Cushing's disease can lead to certain psychological disorders, such as depression and anxiety.

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