What are the signs of Malignant hyperthermia?

Malignant hyperthermia (MH) is a rare, life-threatening condition that can occur in individuals who are susceptible to certain triggering agents, such as certain anesthesia medications. The signs and symptoms of MH can develop rapidly and may include:

- Rapid heart rate (tachycardia): The heart rate may increase significantly, often exceeding 140 beats per minute.

- Muscle rigidity: The muscles of the body may become rigid and stiff, leading to difficulty with breathing and movement.

- Increased body temperature (hyperthermia): The body temperature can rise rapidly, sometimes reaching 104°F (40°C) or higher.

- Sweating: Profuse sweating may occur.

- Metabolic acidosis: The body's pH level may decrease due to the buildup of acidic substances, leading to acidosis.

- Elevated levels of carbon dioxide (hypercapnia): The levels of carbon dioxide in the blood may increase due to impaired breathing and muscle rigidity.

- Changes in muscle tone: The muscles may become weak or paralyzed.

- Increased oxygen demand: The body's oxygen requirements may increase significantly.

- Rapid breakdown of muscle tissue (rhabdomyolysis): The muscle cells may break down, releasing harmful substances into the bloodstream.

- Kidney damage: The kidneys may be damaged due to the release of muscle breakdown products into the bloodstream.

- Seizures: In severe cases, seizures may occur.

- Cardiac arrhythmias: Abnormal heart rhythms may develop.

- Circulatory collapse: The blood pressure may drop dangerously low, leading to circulatory collapse.

If you or someone you know experiences these symptoms during or shortly after anesthesia, it's crucial to seek immediate medical attention. The prompt diagnosis and treatment of MH are essential to improve the chances of a successful outcome.