What is causative agent of appendicitis?
The most common cause of appendicitis is a blockage in the appendix. This blockage can be caused by:
- Fecaliths: Hardened pieces of stool that can become lodged in the appendix.
- Swelling of the lymph nodes: Lymph nodes are small, bean-shaped structures that help fight infection. When they swell, they can block the opening of the appendix.
- Tumors: Benign (non-cancerous) or malignant (cancerous) tumors can also block the appendix.
- Foreign objects: In rare cases, foreign objects such as pins, needles, or seeds can become lodged in the appendix and cause blockage.
Infection: Once the appendix is blocked, bacteria can start to grow and multiply, causing inflammation and infection. The most common bacteria that cause appendicitis are:
- Escherichia coli (E. coli)
- Bacteroides fragilis
- Streptococcus pneumoniae
- Enterococcus faecalis
- Pseudomonas aeruginosa
Other risk factors: Certain factors can increase the risk of developing appendicitis, including:
- Age: Appendicitis is most common in people between the ages of 10 and 30.
- Sex: Men are more likely to develop appendicitis than women.
- Family history: People with a family history of appendicitis are more likely to develop the condition.
- Cystic fibrosis: People with cystic fibrosis are more likely to develop appendicitis.
- Crohn's disease: People with Crohn's disease are more likely to develop appendicitis.
- Immunosuppression: People who are immunosuppressed (have a weakened immune system) are more likely to develop appendicitis.
Symptoms of appendicitis: The most common symptom of appendicitis is pain in the lower right abdomen. Other symptoms can include:
- Nausea
- Vomiting
- Loss of appetite
- Fever
- Chills
- Constipation
- Diarrhea
- Bloating
- Abdominal distension
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