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Exogenic Vs. Endogenic Depression

Exogenous depression (also known as situational or reactive depression) occurs when an external event, such as a job loss, divorce, or death of a loved one, causes depressive symptoms. Endogenous depression (or organic depression) arises internally, due to brain chemistry.

  1. Duration

    • Exogenous depression is a short term reaction to an external situation, while endogenous depression is chronic and possibly a life-long condition.

    Considerations

    • An individual may suffer from both exogenous and endogenous depression at the same time. In fact, the distinction may not be very useful when treating depression. Doctors are now more likely to view the cause of depression as a combination of several factors, including genetic makeup, environment, experiences and brain chemistry.

    Symptoms

    • The symptoms of exogenous and endogenous depression are the same and may include constant sadness, hopelessness, apathy, feelings of guilt or worthlessness, tiredness, insomnia or excessive sleeping, and thoughts of suicide.

    Treatment

    • Exogenous and endogenous depression are treated similarly. Treatment usually includes some combination of psychotherapy ("talk therapy") and antidepressants.

    Warnings

    • Depression is a serious medical condition. If you or some one you know is suffering from symptoms of depression, consult your doctor.

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