Can you get Diphtheria from the vaccine?

The diphtheria vaccine does not cause diphtheria, but it can cause side effects. Side effects of the diphtheria vaccine can include pain, swelling, and redness at the injection site, as well as fever, headache, and muscle aches. These side effects are usually mild and go away within a few days. In rare cases, the diphtheria vaccine can cause a serious allergic reaction called anaphylaxis. This is a medical emergency that can be life-threatening. If you experience any symptoms of anaphylaxis, such as difficulty breathing, swelling of the face or throat, or hives, you should seek medical attention immediately.