What are major phagocytes in blood?

The major phagocytes in blood are:

1. Neutrophils: These are the most abundant type of white blood cell, accounting for 50-70% of all circulating leukocytes. Neutrophils are highly phagocytic and are the first line of defense against bacterial infections. They are particularly effective at engulfing and destroying bacteria, fungi, and other foreign particles.

2. Macrophages: These are large, phagocytic cells that are found in tissues throughout the body. Macrophages are derived from monocytes, which are a type of white blood cell that circulates in the blood. Macrophages can engulf and destroy a wide variety of foreign particles, including bacteria, viruses, fungi, and dead or damaged cells.

3. Eosinophils: These are less common than neutrophils and macrophages, accounting for only 1-3% of all circulating leukocytes. Eosinophils are involved in the body's response to allergic reactions and parasitic infections. They can engulf and destroy parasites, and they also release toxic substances that can damage foreign invaders.

4. Basophils: These are the least common type of white blood cell, accounting for less than 1% of all circulating leukocytes. Basophils are involved in the body's response to allergies and inflammation. They can release histamine and other inflammatory mediators, which can cause symptoms such as sneezing, runny nose, and itchy eyes.

These four types of phagocytes play a vital role in the body's defense against infection and disease. They work together to engulf and destroy foreign invaders and to promote healing and repair.