What is hyper immune globulin?

Hyperimmune globulin (HIG) is a type of immunoglobulin therapy that is used to provide temporary passive immunity against specific infectious diseases. It is made from the blood plasma of people who have high levels of antibodies against a particular disease. When HIG is given to someone who is not immune to a disease, it provides immediate protection by providing the necessary antibodies to fight off the infection.

HIG is used to prevent or treat a variety of diseases, including:

* Hepatitis A

* Hepatitis B

* Rabies

* Tetanus

* Diphtheria

* Varicella-zoster virus (chickenpox)

* Cytomegalovirus (CMV)

* Epstein-Barr virus (EBV)

* Measles

* Mumps

* Rubella

* Polio

* Rotavirus

* SARS-CoV-2 (COVID-19)

HIG is typically given intravenously (IV), but it can also be given intramuscularly (IM) in some cases. The dose and frequency of administration will depend on the specific disease being treated or prevented.

HIG is generally well-tolerated, but it can cause some side effects, such as:

* Fever

* Chills

* Nausea

* Vomiting

* Headache

* Muscle aches

* Joint pain

* Rash

In rare cases, HIG can cause a serious allergic reaction called anaphylaxis. This is a medical emergency and requires immediate treatment.

HIG is an important tool for preventing and treating infectious diseases. It is safe and effective, and it can provide immediate protection against a variety of diseases.