What is a persistent infection?
A persistent infection is an infection that lasts for a long time, often for life. It is caused by a microorganism, such as a virus, bacteria, or fungus, that evades the host's immune system and continues to replicate and cause damage.
Persistent infections can be caused by a variety of factors, such as:
* The microorganism has evolved mechanisms to evade the immune system.
* The host's immune system is compromised or underdeveloped.
* The microorganism is able to form biofilms, which are protective communities of microorganisms that are resistant to antimicrobial agents.
Some examples of persistent infections include:
* HIV/AIDS
* Hepatitis B and C
* Tuberculosis
* Malaria
* Herpes simplex virus
* Epstein-Barr virus
* Cytomegalovirus
* Human papillomavirus
Persistent infections can have a wide range of consequences for the host, including:
* Chronic inflammation
* Tissue damage
* Organ failure
* Cancer
* Death
Treatment of persistent infections is often difficult, as the microorganisms that cause them are often resistant to antimicrobial agents. In some cases, a cure is not possible and the goal of treatment is to manage the symptoms and prevent complications.