ADPKD: Can I Get Pregnant?

Whether or not a person with autosomal dominant polycystic kidney disease (ADPKD) can get pregnant depends on several factors, including the severity of their condition and any associated complications. Here are some considerations:

Kidney Function: ADPKD can affect kidney function over time, and severe kidney disease can impact fertility. If your kidney function is significantly impaired, it may affect your ability to conceive or carry a pregnancy. It's essential to consult with your healthcare provider or a specialist in nephrology and reproductive health to assess your specific situation and determine the potential risks and implications of pregnancy.

Medication: Some medications used to manage ADPKD, such as tolvaptan (Jynarque), can have effects on fertility and pregnancy. Tolvaptan is contraindicated in pregnant women due to its potential to cause fetal harm. If you are considering pregnancy or are currently pregnant, it's crucial to discuss any medications you are taking with your healthcare provider to ensure they are safe for use during pregnancy.

Pregnancy Risks: Women with ADPKD may face certain risks during pregnancy, including:

- Increased risk of preterm delivery: The enlarged kidneys due to ADPKD can put pressure on the uterus, increasing the risk of preterm labor and delivery.

- Preeclampsia: A condition characterized by high blood pressure and protein in the urine, which can develop during pregnancy.

- Gestational diabetes: A type of diabetes that develops during pregnancy, which is more common in women with ADPKD.

- Kidney function decline: Pregnancy can put additional strain on the kidneys, potentially leading to a temporary or permanent decline in kidney function.

It's vital to have a comprehensive discussion with your healthcare provider before planning a pregnancy to carefully assess the risks and benefits, explore your fertility options, and ensure proper prenatal care and monitoring throughout your pregnancy. Your healthcare team can provide guidance and support to help you make informed decisions and manage your condition effectively during pregnancy.