Does ulcerative colitis affect the rectum?

Ulcerative colitis (UC) is a chronic inflammatory disease of the large intestine (colon and rectum). It primarily affects the inner lining of the colon and rectum, causing inflammation and ulceration. Symptoms may include abdominal pain, frequent diarrhea with blood and mucus, rectal urgency, and weight loss. The severity of symptoms can vary widely from person to person. In severe cases, UC can also affect other parts of the body, such as the skin, eyes, and joints.