Can ulcerative colitis cause a low white blood cell count?

In most cases, ulcerative colitis does not cause a low white blood cell count (leukopenia). However, in severe cases of ulcerative colitis, where there is extensive inflammation and tissue damage, the body may struggle to produce enough white blood cells, leading to leukopenia. If a person with ulcerative colitis experiences leukopenia, it's important for the doctor to assess the severity of the condition and consider any underlying factors or complications.