What are the early symptoms of primary biliary cirrhosis?

Primary biliary cirrhosis (PBC) often does not cause any symptoms in its early stages. Sometimes early symptoms may be non-specific and include:

1. Itching: This is often one of the first symptoms, often starting on the palms of the hands and soles of the feet, and can be particularly noticeable at night.

2. Fatigue and Weakness: Feeling very tired and having low energy levels. Some people may feel constantly exhausted.

3. Dry Eyes and Mouth: A reduced production of tears and saliva, which can cause irritation and discomfort in the eyes and mouth.

4. Joint Pain: Joint pain and swelling may occur, particularly in the small joints of the hands and feet.

5. Pale Stools and Dark Urine: Changes in stool and urine color can be a result of reduced bile flow. Stools may become lighter in color and urine might appear darker.

6. Skin Discoloration: The skin may become slightly yellow (jaundice), especially in the whites of the eyes.

7. Abdominal Discomfort: A mild, dull ache in the upper right abdomen might occur, although severe abdominal pain is not typical in early stages.

8. Nausea and Indigestion: Upset stomach, heartburn, and a general sense of discomfort or fullness after meals.

9. Loss of Appetite: A reduced desire for food can lead to weight loss.

10. Hair Loss: Reduced hair density or hair loss might be noticed.

It's important to note that not everyone experiences these symptoms, and their severity can vary from person to person. If you are concerned about any of these symptoms, it is recommended to consult with a healthcare professional for proper evaluation and diagnosis.