How C3 Glomerulopathy Affects Your Kidneys

C3 glomerulopathy is an autoimmune disease that affects the kidneys. It is a rare condition, but it can lead to kidney failure.

C3 glomerulopathy occurs when the body's immune system attacks the kidneys. The immune system produces a protein called C3, which is involved in the body's defense against infection. In C3 glomerulopathy, the C3 protein is deposited in the kidneys, where it can cause inflammation and damage to the kidney tissue.

The symptoms of C3 glomerulopathy can include:

* Swelling in the face, hands, and feet

* High blood pressure

* Foamy urine

* Nausea and vomiting

* Fatigue

* Weight loss

* Kidney failure

C3 glomerulopathy is a serious condition, but it can be treated. Treatment options include medications to suppress the immune system, dialysis, and kidney transplantation.

How does C3 glomerulopathy affect the kidneys?

C3 glomerulopathy affects the kidneys by causing inflammation and damage to the kidney tissue. This can lead to a number of problems, including:

* Proteinuria: Proteinuria is the presence of protein in the urine. This can be a sign of kidney damage.

* Hematuria: Hematuria is the presence of blood in the urine. This can also be a sign of kidney damage.

* Casts: Casts are formed when protein and other substances are deposited in the kidney tubules. This can block the flow of urine and cause kidney damage.

* Scarring: Scarring of the kidney tissue can occur as a result of inflammation and damage. This can lead to kidney failure.

C3 glomerulopathy can also lead to a number of other complications, including:

* High blood pressure

* Heart disease

* Stroke

* Infection

* Death

What is the outlook for people with C3 glomerulopathy?

The outlook for people with C3 glomerulopathy depends on the severity of the disease and the individual's response to treatment. With early diagnosis and treatment, many people with C3 glomerulopathy are able to live full and active lives.