What are the subdivisons of renal tubule?
The renal tubules have the following four subdivisions:
1. Proximal convoluted tubule (PCT):
- First portion of the renal tubule
- Highly convoluted and lined by brush border cells
- Responsible for reabsorption of various solutes, including glucose, amino acids, sodium, and water.
2. Proximal straight tubule (PST):
- Continues from PCT and descends towards the medulla
- Lined by simple cuboidal cells
- Involved in additional reabsorption of solutes and water
3. Loop of Henle:
- Consists of a descending limb and an ascending limb
- Descending limb: Thin and lined by simple squamous cells. Responsible for reabsorption of water
- Ascending limb: Thick and lined by cuboidal cells. Reabsorbs sodium and chloride, creating a hypertonic environment in the medulla
4. Distal convoluted tubule (DCT):
- Located after the loop of Henle
- Convoluted and lined by cuboidal cells with prominent mitochondria
- Involved in fine regulation of water and sodium balance, as well as secretion of potassium and hydrogen ions