What is the Autopsy finding in essential hypertension kidney?

Autopsy Findings in Essential Hypertension Kidney

* Gross

* Kidneys are typically enlarged and firm, with a red or purple appearance.

* The renal capsule may be thickened and adherent to the underlying parenchyma.

* On cut surface, the cortex may be thin and pale, while the medulla may be congested.

* There may be evidence of arteriolosclerosis and interstitial fibrosis.

* Microscopic

* The glomeruli may show evidence of hypertrophy, sclerosis, and/or necrosis.

* The renal tubules may be atrophic and may contain protein casts.

* The interstitium may be fibrotic and may contain inflammatory infiltrates.

* The arteries and arterioles may show evidence of arteriosclerosis, with thickening of the intima and media.

* Immunofluorescence

* Immunofluorescence staining may reveal the presence of immune complexes in the glomeruli.

* Electron Microscopy

* Electron microscopy may reveal changes in the basement membrane of the glomeruli and renal tubules.